Incidence and determinants of perinatal mortality among women with obstructed labour in eastern Uganda: a prospective cohort study

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dc.contributor.authorMusaba, Milton W.
dc.contributor.authorNdeezi, Grace
dc.contributor.authorBarageine, Justus K.
dc.contributor.authorWeeks, Andrew D.
dc.contributor.authorWandabwa, Julius N.
dc.contributor.authorMukunya, David
dc.contributor.authorWaako, Paul
dc.contributor.authorOdongkara, Beatrice
dc.contributor.authorArach, Agnes
dc.contributor.authorTulya-muhika Mugabe, Kenneth
dc.contributor.authorKasede Napyo, Agnes
dc.contributor.authorNankabirwa, Victoria
dc.contributor.authorTumwine, James K.
dc.date.accessioned2023-08-21T08:11:03Z
dc.date.available2023-08-21T08:11:03Z
dc.date.issued2021
dc.descriptionResearch article
dc.description.abstractBackground: In Uganda, the incidence and determinants of perinatal death in obstructed labour are not well documented. We determined the incidence and determinants of perinatal mortality among women with obstructed labour in Eastern Uganda. Methods: Between July 2018 and September 2019, 584 with obstructed labour were recruited and followed up to the 7th day postnatal. Information on maternal characteristics, obstetric factors and laboratory parameters was collected. Each patient received the standard perioperative care. We used a generalized linear model for the Poisson family, with a log link and robust variance estimation to determine the association between the exposure variables and perinatal death. Results: Of the 623 women diagnosed with obstructed labour, 584 met the eligibility criteria. There were 24 fresh still births (FSB) and 32 early neonatal deaths (ENND) giving an FSB rate of 43.8 (95% CI 28.3–64.4) deaths per 1000 total births; early neonatal death rate of 58.4 (95% CI 40.3–81.4) deaths per 1000 and an overall perinatal mortality rate of 102.2 (95% CI 79.4–130.6) deaths in the first 7 days of life. A mother being referred in active labour adjusted risk ratio of 2.84 (95% CI: 1.35–5.96) and having high blood lactate levels at recruitment adjusted risk ratio 2.71 (95% CI: 1.26–4.24) were the determinants of perinatal deaths. Conclusions: The incidence of perinatal death was four times the regional and national average. Babies to women referred in active labour and those with high maternal blood lactate were more likely to die. Keywords: Obstructed labour, Perinatal death, Determinants, Lactate
dc.description.sponsorshipMbale Regional Referral and Teaching Hospital, Makerere University College of Health Sciences, University of Liverpool/Liverpool Women’s Hospital, Busitema University
dc.identifier.citationMusaba, M. W., . . . et al. (2021). Incidence and determinants of perinatal mortality among women with obstructed labor in eastern Uganda: a prospective cohort study. Maternal Health, Neonatology, and Perinatology (2021) 7:13. https://doi.org/10.1186/s40748-021-00133-7
dc.identifier.urihttps://doi.org/10.60682/cdvh-wv42
dc.language.isoen
dc.publisherSpringer Nature
dc.subjectResearch Subject Categories::MEDICINE::Surgery::Obstetrics and women's diseases::Obstetrics and gynaecology
dc.titleIncidence and determinants of perinatal mortality among women with obstructed labour in eastern Uganda: a prospective cohort study
dc.typeArticle
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