Evaluation of Phytochemical Constituents of Rotheca Myricoides (Hocsht) For the Management of Syphilis in Humans and Formulation of An Herbal Remedy
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Date
2023
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Busitema University
Abstract
Syphilis is a multistage acute and chronic sexually transmitted infection (STI) that is caused by the bacterium Treponema pallidum subspecies pallidum that produces skin and mucous membrane lesions at the onset of the infection. Syphilis globally claims over 58% of the population per year in the world as per 2021.Rotheca myricoides is used locally for various medicinal purposes by traditionalists and herbalists in Uganda. Plants products have been used since ancient times in the management of various conditions. Rotheca myricoides (Hochst) is used in the management of diabetes, treatment of malaria, cancer, gastrointestinal disorders, asthma, spleen enlargement, persistent fever, headache, dysentery, diarrhea, syphilis, snakebite, impotence, eye problems, typhoid, cough, tonsillitis, rheumatism gonorrhea. The objective of this study is to evaluate the phytochemical constituents of Rotheca myricoides and its efficacy on the management of syphilis. The crude extract of Rotheca myricoides was subjected to preliminary phytochemical screening and antimicrobial tests. The phytochemical tests were carried out using standard methods of analysis and these investigations revealed the presence of tannins, saponins, flavonoids, phenols, quinones and alkaloids while terpenoids, glycosides and steroids were not present in the crude extract. Herbal syrup was formulated by mixing different active ingredients and a few of its physiochemical properties were determined. The toxicity profile of R. myricoides traditional therapy must first be determined as while as the appropriate quantity for the full dose. The bacterial assay should be done to find the minimum inhibitory concentration of R. myricoides extract on T. pallidum.
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Nambala, O. (2023). Evaluation of phytochemical constituents of Rotheca myricoides (Hocsht) for the management of syphilis in humans and formulation of an herbal remedy. [Undergraduate, Research Report]. Busitema University.