Phytochemical analysis and antifungal activity of Conyza sumatrensis root extract for management of ringworm infection.
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Date
2024
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Busitema University
Abstract
Ringworm causing a red ring rash is a common fungal infection of human skin. It is caused by a group of fungi like Microsporum canls and Aspergillus niger which affect people of all ages and it is mainly managed by antifungal agents. However, the current antifungal drugs are becoming ineffective because of antifungal resistance and alternatives medications derived from medicinal plants are being considered. C. Sumantresis, a plant with a long history of traditional use in the management of ringworm was the focus of this study with the aim of profiling its phytochemical and antifungal properties for management of ringworm. Alcoholic root extract of C. Sumantresis was subjected to different phytochemical analysis to investigate active constituents present, quantified with different standards whose calibration curves were used to determine the concentration of specific metabolites in the extract. Fungal culture was performed on Aspergillus niger to determine the antifungal activity of the extract. The results indicated that the extract had higher alkaloids, moderate flavonoids and relatively low tannins and phenols. Antifungal activity showed total inhibition of fungal growth at the concentration of 7mg/ml of the extract reflecting therapeutic properties of the extract. The findings of this study suggest that C. Sumantresis is a promising natural resource for the development of antifungal medications and warrant further investigation.
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Walakila, F. W. (2024). Phytochemical analysis and antifungal activity of Conyza sumatrensis root extract for management of ringworm infection. [Undergraduate, Research Report]. Busitema University.