Quantitative phytochemical analysis of euclea racemosa as a potential anti-bacterial herbal remedy for management of pneumonia
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Date
2024
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Busitema University
Abstract
Introduction: Pneumonia is a respiratory tract infection which is caused by microorganisms resulting into inflammations due to fluid filling in the air sac in either both or one of the lungs. Pneumonia kills more children than any other infectious disease, claiming the lives of close to 2,000 children everyday world wide. Objective: To quantitatively analyze the Phytochemistry of Euclea racemosa for potential antibacterial activity and formulation of an herbal remedy for management of respiratory tract infections. Materials and methods: The phytochemical analysis of Euclea racemosa that belongs to kingdom plantae, Order Ericales, family Ebenaceae, Genius Euclea, species Euclea Racemosa, was examined using organic extracts and aqueous extracts of the leaves of Euclea racemosa. Results: The organic extracts used in investigation of phytochemical and confirmed alkaloids (214.87mg/g), flavonoids (30.3mg/g), tannins (136.5mg/g), phenols (30.2mg/g), glycosides, saponins and as well antibacterial activity investigated on Escherichia coli, Pseudomonas aeruginosa and staphylococcus aureus evidenced by the percentage rate inhibition. Conclusion: The extracts showed high inhibition on E. coli than it was on pseudomonas aeruginosa, therefore the antimicrobial activity of E. racemosa is most effect on E. coli. The ability of E. racemosa to show antimicrobial activity may be attributed to the presence of flavonoids, alkaloids, phenolics, tannins, glycosides and saponins which were confirmed to be biologically active ingredients during the phytochemical analysis of the crude extract.
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Nangoli, C. (2024). Quantitative phytochemical analysis of Euclea racemosa as a potential anti-bacterial herbal remedy for management of pneumonia [Undergraduate, Research Report]. Busitema University.